Pengfei Yu Selected Research

NSK-01105

3/2015	NSK-01105 inhibits proliferation and induces apoptosis of prostate cancer cells by blocking the Raf/MEK/ERK and PI3K/Akt/mTOR signal pathways.
1/2014	NSK-01105, a novel sorafenib derivative, inhibits human prostate tumor growth via suppression of VEGFR2/EGFR-mediated angiogenesis.

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Pengfei Yu Research Topics

Disease

36	Neoplasms (Cancer) 02/2022 - 04/2009
21	Stomach Neoplasms (Stomach Cancer) 01/2022 - 08/2013
10	Neoplasm Metastasis (Metastasis) 01/2022 - 10/2010
8	Inflammation (Inflammations) 12/2021 - 10/2009
5	Hepatocellular Carcinoma (Hepatoma) 05/2018 - 04/2009
4	Adenocarcinoma 10/2021 - 08/2017
4	Pancreatitis 01/2017 - 08/2014
3	Body Weight (Weight, Body) 06/2021 - 06/2013
3	Intervertebral Disc Displacement (Herniated Disc) 01/2021 - 07/2020
3	Melanoma (Melanoma, Malignant) 01/2020 - 01/2019
3	Edema (Dropsy) 08/2016 - 04/2012
3	Breast Neoplasms (Breast Cancer) 07/2016 - 04/2009
2	Pancreatic Neoplasms (Pancreatic Cancer) 02/2022 - 08/2017
2	Intervertebral Disc Degeneration 01/2022 - 01/2021
2	Infections 01/2020 - 01/2008
2	Peritoneal Neoplasms 01/2018 - 10/2017
2	Prostatic Neoplasms (Prostate Cancer) 08/2017 - 03/2015
2	Alzheimer Disease (Alzheimer's Disease) 01/2017 - 03/2013
2	Hypoxia (Hypoxemia) 03/2015 - 07/2012
2	Brain Ischemia (Cerebral Ischemia) 03/2015 - 01/2012
2	Wounds and Injuries (Trauma) 01/2014 - 04/2012
2	Parkinson Disease (Parkinson's Disease) 06/2013 - 02/2013
2	Foreign Bodies (Foreign Body) 06/2013 - 02/2013
1	Multiple System Atrophy 06/2022
1	Acute Lung Injury 06/2022
1	Thrombotic Microangiopathies 12/2021
1	Emphysema 10/2021
1	Idiopathic Pulmonary Fibrosis 10/2021
1	Angina Pectoris 10/2021
1	Coronary Disease (Coronary Heart Disease) 10/2021
1	Non-alcoholic Fatty Liver Disease 02/2021
1	Liver Diseases (Liver Disease) 01/2021

Drug/Important Bio-Agent (IBA)

8	Pharmaceutical PreparationsIBA 06/2022 - 02/2013
8	Proteins (Proteins, Gene)FDA Link 02/2022 - 04/2009
6	Therapeutic UsesIBA 06/2022 - 04/2009
3	NF-kappa B (NF-kB)IBA 01/2020 - 04/2009
3	Messenger RNA (mRNA)IBA 07/2016 - 04/2009
3	trioctyl phosphine oxide (TOPO)IBA 01/2015 - 01/2014
2	Fatty Acids (Saturated Fatty Acids)IBA 02/2021 - 01/2017
2	cholesterol 25-hydroxylaseIBA 01/2021 - 01/2019
2	bisphenol AIBA 09/2020 - 01/2017
2	Toll-Like Receptor 4IBA 01/2020 - 10/2013
2	Interferon Type IIBA 01/2020 - 01/2019
2	EnzymesIBA 01/2020 - 01/2016
2	Ganciclovir (Cytovene)FDA LinkGeneric 01/2020 - 01/2008
2	Biological ProductsIBA 12/2019 - 10/2015
2	Peptides (Polypeptides)IBA 05/2018 - 01/2018
2	AntigensIBA 05/2018 - 11/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2018 - 10/2013
2	Interleukin-10 (Interleukin 10)IBA 03/2018 - 10/2013
2	InterleukinsIBA 03/2018 - 10/2013
2	MicroRNAs (MicroRNA)IBA 01/2018 - 03/2015
2	LeptinIBA 01/2018 - 11/2016
2	AdipokinesIBA 01/2018 - 11/2016
2	Estrogen ReceptorsIBA 01/2018 - 10/2009
2	Cadherins (E-Cadherin)IBA 08/2017 - 01/2016
2	Amylases FDA Link 08/2016 - 08/2014
2	NSK-01105IBA 03/2015 - 01/2014
2	ProlactinIBA 06/2013 - 02/2013
2	Polyglactin 910IBA 06/2013 - 02/2013
2	SodiumIBA 06/2013 - 02/2013
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2009 - 04/2009
2	MatrinesIBA 04/2009 - 04/2009
1	CateninsIBA 06/2022
1	CalpainIBA 06/2022
1	Peroxidase (Myeloperoxidase)IBA 06/2022
1	abemaciclibIBA 01/2022
1	tetrandrineIBA 01/2022
1	Chimeric Antigen ReceptorsIBA 01/2022
1	neodymium pyrocatechin disulfonate (NPD)IBA 01/2022
1	cyclopropapyrroloindoleIBA 10/2021
1	Carbon MonoxideIBA 10/2021
1	Rheumatoid FactorIBA 10/2021
1	LipidsIBA 10/2021
1	CholesterolIBA 10/2021
1	AntibodiesIBA 09/2021
1	LPM4870108IBA 06/2021
1	Triglycerides (Triacylglycerol)IBA 02/2021
1	oil red OIBA 02/2021
1	bisphenol FIBA 02/2021
1	4,4- difluoro- 1,3,5,7,8- pentamethyl- 4- bora- 3a,4a- diaza- s- indaceneIBA 02/2021
1	XELOXIBA 01/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021
1	Capecitabine (Xeloda)FDA Link 01/2021
1	Albumin-Bound Paclitaxel FDA Link 01/2021
1	130-nm albumin-bound paclitaxelIBA 01/2021
1	Yiqi Huoxue recipeIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021

Therapy/Procedure

13	Drug Therapy (Chemotherapy) 01/2022 - 08/2013
11	Therapeutics 01/2022 - 01/2008
7	Gastrectomy 01/2022 - 08/2013
5	Chinese Traditional Medicine (Traditional Chinese Medicine) 10/2021 - 07/2017
2	Lymph Node Excision (Lymph Node Dissection) 01/2022 - 10/2021
2	Aftercare (After-Treatment) 10/2021 - 01/2021
2	Adjuvant Chemotherapy 01/2021 - 10/2014
2	Cytoreduction Surgical Procedures 11/2020 - 06/2014
2	Metastasectomy 01/2018 - 10/2017
2	Liver Transplantation 11/2013 - 01/2008
1	Adjuvant Radiotherapy 10/2021
1	Chemoradiotherapy 10/2021